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Albert Adam Selected Research

omapatrilat

10/2005Vasopeptidase inhibition peri- and post-MI in Zucker insulin resistant rats: effect on MI size, arrhythmias, remodeling, function and fetal gene expression.
3/2005Effects of the vasopeptidase inhibitor omapatrilat on peri- and postmyocardial infarction in Zucker lean rats.
12/2003Comparative effects of a vasopeptidase inhibitor vs. an angiotensin converting enzyme inhibitor on cardiomyocyte apoptosis in rats with heart failure.
9/2002Comparison of the effects of omapatrilat and lisinopril on circulating neurohormones and cytokines in patients with chronic heart failure.
5/2002Comparison of the effects of an angiotensin-converting enzyme inhibitor and a vasopeptidase inhibitor after myocardial infarction in the rat.
1/2002Effects of captopril and omapatrilat on early post-myocardial infarction survival and cardiac hemodynamics in rats: interaction with cardiac cytokine expression.

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Albert Adam Research Topics

Disease

9Angioedema
11/2011 - 06/2002
7Myocardial Infarction
03/2005 - 01/2002
6Inflammation (Inflammations)
02/2010 - 07/2002
6Hypotension (Low Blood Pressure)
05/2008 - 01/2002
5Fibrosis (Cirrhosis)
12/2003 - 01/2002
4Heart Failure
12/2003 - 04/2002
4Cicatrix (Scar)
12/2003 - 01/2002
3Hypertrophy
05/2002 - 01/2002
2Anaphylaxis (Anaphylactic Shock)
08/2010 - 10/2007
2Transfusion Reaction
05/2008 - 09/2004
2Tics (Tic)
04/2006 - 09/2005
2Insulin Resistance
10/2005 - 03/2005
2Infarction (Infarctions)
03/2005 - 05/2002
2Ischemia
02/2005 - 10/2003
2Enterocolitis
12/2002 - 07/2002
1Diabetes Complications
04/2010
1Hyperalgesia
02/2010
1Acute Pain
02/2010
1Pain (Aches)
02/2010
1Hemorrhage
05/2008
1End Stage Liver Disease
05/2008
1Surgical Blood Loss
05/2008
1Hypersensitivity (Allergy)
03/2008
1Hereditary Angioedemas
02/2008
1Edema (Dropsy)
01/2008
1Wounds and Injuries (Trauma)
11/2006
1Cardiovascular Diseases (Cardiovascular Disease)
10/2005
1Amniotic Fluid Embolism
10/2005
1Pathologic Processes
09/2005
1Arthritis (Polyarthritis)
08/2005
1Cardiomegaly (Heart Hypertrophy)
03/2005
1Right Ventricular Hypertrophy
03/2005
1Reactive Arthritis (Reiter Disease)
09/2004
1Left Ventricular Hypertrophy (Ventricular Hypertrophy, Left)
07/2003
1Hemolytic-Uremic Syndrome
11/2002
1Dilated Cardiomyopathy (Cardiomyopathy, Congestive)
09/2002
1Ischemic Stroke
06/2002

Drug/Important Bio-Agent (IBA)

17Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA
11/2011 - 01/2002
15BradykininIBA
11/2011 - 06/2002
9Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme)IBA
04/2010 - 01/2002
7KininsIBA
04/2010 - 09/2004
7Vasopeptidase InhibitorsIBA
10/2005 - 01/2002
6omapatrilatIBA
10/2005 - 01/2002
5Peptides (Polypeptides)IBA
03/2008 - 09/2005
5CytokinesIBA
09/2002 - 01/2002
4X-Pro aminopeptidase (aminopeptidase P)IBA
11/2011 - 01/2008
4Neprilysin (Neutral Endopeptidase)IBA
04/2010 - 01/2002
4Metalloproteases (Metalloproteinases)IBA
02/2008 - 10/2002
3High-Molecular-Weight Kininogen (Kininogen, High Molecular Weight)IBA
08/2005 - 07/2002
3Kininogens (Kininogen)IBA
08/2005 - 07/2002
3Peptidoglycan (Murein)IBA
08/2005 - 07/2002
3Polysaccharides (Glycans)IBA
08/2005 - 07/2002
3Captopril (Capoten)FDA LinkGeneric
12/2003 - 01/2002
2Antihypertensive Agents (Antihypertensives)IBA
11/2011 - 05/2008
2Peptide Hydrolases (Proteases)FDA Link
04/2010 - 11/2006
2Substance PIBA
01/2008 - 11/2006
2amastatinIBA
04/2006 - 09/2005
2lysyllysine (Lys-Lys)IBA
04/2006 - 09/2005
2PolymersIBA
12/2002 - 07/2002
2Lisinopril (Prinivil)FDA LinkGeneric
11/2002 - 09/2002
2Probucol (Lorelco)FDA Link
05/2002 - 01/2002
2AntioxidantsIBA
05/2002 - 01/2002
1Heparin (Liquaemin)FDA LinkGeneric
08/2010
1Chondroitin Sulfates (Chondroitin Sulfate)IBA
08/2010
1KetorolacIBA
02/2010
1G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA
02/2010
1ProstaglandinsIBA
02/2010
1LigandsIBA
02/2010
1EnzymesIBA
05/2008
1Lysine Carboxypeptidase (Carboxypeptidase N)IBA
02/2008
1AndrogensIBA
02/2008
1AntigensIBA
01/2008
1Dipeptidyl Peptidase 4 (Dipeptidyl Peptidase IV)IBA
01/2008
1Interleukin-1beta (Interleukin 1 beta)IBA
11/2006
1Bovine Serum AlbuminIBA
11/2006
1B-9958IBA
04/2006
1CD13 Antigens (Alanine Aminopeptidase)IBA
04/2006
1Arginine (L-Arginine)FDA Link
04/2006
1Chromogenic CompoundsIBA
04/2006
1Insulin (Novolin)FDA Link
10/2005
1Plasma KallikreinIBA
09/2004
1Monoclonal AntibodiesIBA
09/2004
1des-Arg(9)- bradykininIBA
10/2003
1Staphylococcal Protein A (Protein A)IBA
11/2002
1Mitomycin (Mitomycin-C)FDA LinkGeneric
11/2002
1Endothelin-1 (Endothelin 1)IBA
09/2002
1Neurotransmitter Agents (Neurotransmitter)IBA
09/2002
1Natriuretic PeptidesIBA
09/2002
1FibrinolysinFDA Link
06/2002

Therapy/Procedure

3Therapeutics
11/2002 - 09/2002
2Renal Dialysis (Hemodialysis)
03/2008 - 10/2007
2Ligation
07/2003 - 05/2002
1Minor Surgical Procedures (Minor Surgery)
02/2010
1Resuscitation
05/2008
1Transplantation
05/2008
1Liver Transplantation
05/2008
1Blood Transfusion (Blood Transfusions)
05/2008
1Intraperitoneal Injections
08/2005
1Prostatectomy (Retropubic Prostatectomy)
09/2004
1Hemodilution
09/2004